{"id":6642,"date":"2023-04-11T13:00:46","date_gmt":"2023-04-11T12:00:46","guid":{"rendered":"https:\/\/www.njoftime.co\/blog\/?p=6642"},"modified":"2023-04-11T13:04:44","modified_gmt":"2023-04-11T12:04:44","slug":"mekanizmi-i-inteligjences-artificiale-mund-te-zbuloje-mutacione-ne-tumoret-e-trurit-brenda-90-sekondave","status":"publish","type":"post","link":"https:\/\/www.njoftime.co\/blog\/mekanizmi-i-inteligjences-artificiale-mund-te-zbuloje-mutacione-ne-tumoret-e-trurit-brenda-90-sekondave.html","title":{"rendered":"Mekanizmi i inteligjenc\u00ebs artificiale mund t\u00eb zbuloj\u00eb mutacione n\u00eb tumoret e trurit brenda 90 sekondave"},"content":{"rendered":"\n

P\u00ebrparimet n\u00eb algoritmet e m\u00ebsimit t\u00eb thell\u00eb t\u00eb inteligjenc\u00ebs artificiale (AI) po ndihmojn\u00eb n\u00eb p\u00ebrshpejtimin e neuroshkenc\u00ebs, mjek\u00ebsis\u00eb s\u00eb personalizuar dhe onkologjis\u00eb precize. Nj\u00eb studim i fundit i publikuar n\u00eb \u2018\u2018Nature Medicine\u2018\u2018 tregon se si nj\u00eb mjet i ri diagnostikues i AI i quajtur DeepGlioma<\/strong> mund t\u00eb p\u00ebrdor\u00eb imazhe t\u00eb shpejta p\u00ebr t\u00eb identifikuar mutacionet gjenetike nga mostrat e tumorit t\u00eb trurit n\u00eb m\u00eb pak se 90 sekonda me sakt\u00ebsi t\u00eb lart\u00eb.<\/p>\n\n\n\n

Neurokirurgu i Shkoll\u00ebs Mjek\u00ebsore t\u00eb Universitetit t\u00eb Mi\u00e7iganit dhe asistent profesor i neurokirurgjis\u00eb Todd Hollon, drejtoi studimin me studiuesit q\u00eb bashk\u00ebpunuan me Universitetin e Mi\u00e7iganit, Universitetin e Nju Jorkut, Universitetin e Kalifornis\u00eb, San Francisko, Universitetin Mjek\u00ebsor t\u00eb Vjen\u00ebs, Spitalin Universitar t\u00eb K\u00ebln dhe Invenio Imaging.<\/p>\n\n\n\n

“vendosja n\u00eb testet diagnostike molekulare \u00ebsht\u00eb e pabarabart\u00eb p\u00ebr pacient\u00ebt q\u00eb marrin kujdes p\u00ebr tumoret e trurit,” shkroi Dr. Hollon n\u00eb bashk\u00ebpunim me koleg\u00ebt e tij studiues. “DeepGlioma<\/strong> mund t\u00eb p\u00ebrmir\u00ebsoj\u00eb testimin molekular duke ofruar testime t\u00eb shpejta molekulare, duke i lejuar klinicist\u00ebt t\u00eb p\u00ebrqendrohen vet\u00ebm n\u00eb konfirmimin e mutacioneve m\u00eb t\u00eb mundshme diagnostike, n\u00eb vend q\u00eb t\u00eb p\u00ebrdorin nj\u00eb hyrje diagnostike fizike.”<\/p>\n\n\n\n

Gliomat jan\u00eb tumore q\u00eb formohen kur qelizat gliale n\u00eb tru ose n\u00eb palc\u00ebn kurrizore rriten jasht\u00eb kontrollit. Tre llojet e qelizave gliale jan\u00eb astrocitet, oligodendrocitet dhe qelizat epidermale. Glia, e njohur edhe si neuroglia ose glia, do t\u00eb thot\u00eb “ngjit\u00ebs” n\u00eb greqisht dhe u krijua n\u00eb 1856 nga patologu i famsh\u00ebm gjerman Rudolph Virchow<\/strong>, i cili konsiderohet nj\u00eb pionier n\u00eb patologjin\u00eb moderne me kontributin e tij n\u00eb teorin\u00eb e qelizave.<\/p>\n\n\n\n

Trajtimi i gliomave varet nga grada e tyre. Organizata Bot\u00ebrore e Sh\u00ebndet\u00ebsis\u00eb (OBSH) ka kat\u00ebr shkall\u00eb p\u00ebr tumoret e trurit q\u00eb variojn\u00eb nga shkall\u00ebt m\u00eb t\u00eb ul\u00ebta me rritje t\u00eb ngadalt\u00eb (shkalla I, shkalla II) deri te shkall\u00ebt m\u00eb t\u00eb larta me rritje m\u00eb t\u00eb shpejt\u00eb (shkalla III, shkalla IV). P\u00ebr shembull, glioblastoma, e quajtur edhe GBM ose glioblastoma multiforme, nj\u00eb lloj kanceri ve\u00e7an\u00ebrisht agresiv i trurit q\u00eb prek astrocitet, \u00ebsht\u00eb nj\u00eb glioma e shkall\u00ebs IV.<\/p>\n\n\n\n

“DeepGlioma<\/strong> parashikoi me sakt\u00ebsi mutacionet IDH, kodimin 1p19q dhe mutacionet ATRX pa nevoj\u00ebn p\u00ebr hibridizimin fluoreshent in situ ose sekuenc\u00ebn gjenetike, duke mund\u00ebsuar n\u00ebnklasifikimin e automatizuar molekular t\u00eb gliomave difuze sipas sistemit t\u00eb klasifikimit t\u00eb OBSH-s\u00eb,” raportuan shkenc\u00ebtar\u00ebt.<\/p>\n\n\n\n

Diagnostifikimi molekular ose patologjia molekulare analizon sekuencat e kodit gjenetik (ADN ose ARN) n\u00eb qeliza p\u00ebr t\u00eb gjetur nj\u00eb mutacion gjenik t\u00eb trash\u00ebguar ose t\u00eb fituar t\u00eb lidhur me nj\u00eb s\u00ebmundje t\u00eb caktuar. Diagnostifikimi molekular mund t\u00eb identifikoj\u00eb infeksione ose faktor\u00eb rreziku gjenetik p\u00ebr s\u00ebmundje t\u00eb caktuara. Testet molekulare i lejojn\u00eb mjek\u00ebt t\u00eb ofrojn\u00eb trajtim m\u00eb t\u00eb synuar p\u00ebrmes mjek\u00ebsis\u00eb precize bazuar n\u00eb variacionet gjenomike kundrejt nj\u00eb qasjeje “nj\u00eb madh\u00ebsi p\u00ebr t\u00eb gjith\u00eb” p\u00ebr trajtimin e kancerit.<\/p>\n\n\n\n

\u201cKlasifikimi molekular ka transformuar menaxhimin e tumoreve t\u00eb trurit, duke mund\u00ebsuar prognoz\u00eb m\u00eb t\u00eb sakt\u00eb dhe trajtim t\u00eb personalizuar\u201d, shkruan studiuesit. “Megjithat\u00eb, testimi i hersh\u00ebm i diagnostikimit molekular p\u00ebr pacient\u00ebt me tumore t\u00eb trurit \u00ebsht\u00eb i kufizuar, duke komplikuar trajtimin kirurgjik dhe ndihm\u00ebs dhe duke penguar regjistrimin n\u00eb provat klinike.”<\/p>\n\n\n\n

DeepGlioma<\/strong> p\u00ebrdor metoda t\u00eb vizionit kompjuterik t\u00eb bazuar n\u00eb t\u00eb m\u00ebsuarit e thell\u00eb t\u00eb AI, t\u00eb p\u00ebrb\u00ebr\u00eb nga dy module t\u00eb para-trajnuara, nj\u00eb kodues vizual dhe nj\u00eb kodues gjenetik, t\u00eb cilat jan\u00eb t\u00eb integruara p\u00ebrmes nj\u00eb mekanizmi v\u00ebmendjeje p\u00ebr klasifikimin e imazheve.<\/p>\n\n\n\n

“Pengesat ndaj diagnoz\u00ebs molekulare mund t\u00eb \u00e7ojn\u00eb n\u00eb kujdes jo optimal p\u00ebr pacient\u00ebt me tumor t\u00eb trurit, duke komplikuar parashikimin prognostik, marrjen e vendimeve kirurgjikale, shtrirjen e objektivave t\u00eb rezeksionit, zgjedhjen e regjimeve ndihm\u00ebse t\u00eb kemoradioterapis\u00eb dhe regjistrimin e provave klinike. ,” shkruajn\u00eb studiuesit.<\/p>\n\n\n\n

Dr. Hollon dhe ekipi i tij studiues vendos\u00ebn t\u00eb arrijn\u00eb performanc\u00ebn optimale n\u00eb klasifikimin TN duke p\u00ebrdorur kombinimin e imazheve dhe t\u00eb dh\u00ebnave gjenomike publike n\u00eb shkall\u00eb t\u00eb gjer\u00eb.<\/p>\n\n\n\n

“K\u00ebtu, ne propozojm\u00eb dhe v\u00ebrtetojm\u00eb n\u00eb m\u00ebnyr\u00eb prospektive nj\u00eb qasje t\u00eb bazuar n\u00eb AI p\u00ebr t\u00eb thjeshtuar klasifikimin molekular t\u00eb gliomave difuze p\u00ebrmes analiz\u00ebs s\u00eb imazhit t\u00eb automatizuar t\u00eb imazhit t\u00eb shpejt\u00eb optik t\u00eb ekzemplar\u00ebve t\u00eb fresk\u00ebt dhe t\u00eb pap\u00ebrpunuar kirurgjikale,” ndan\u00eb shkenc\u00ebtar\u00ebt.<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

P\u00ebrparimet n\u00eb algoritmet e m\u00ebsimit t\u00eb thell\u00eb t\u00eb inteligjenc\u00ebs artificiale (AI) po ndihmojn\u00eb n\u00eb p\u00ebrshpejtimin e neuroshkenc\u00ebs, mjek\u00ebsis\u00eb s\u00eb personalizuar dhe onkologjis\u00eb precize. Nj\u00eb studim i fundit i publikuar n\u00eb \u2018\u2018Nature Medicine\u2018\u2018 tregon se si nj\u00eb mjet i ri diagnostikues i AI i quajtur DeepGlioma mund t\u00eb p\u00ebrdor\u00eb imazhe t\u00eb shpejta p\u00ebr t\u00eb identifikuar mutacionet […]<\/p>\n","protected":false},"author":1,"featured_media":6643,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[583],"tags":[815,816],"class_list":{"0":"post-6642","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-shendetsore","8":"tag-deepglioma","9":"tag-medicine"},"yoast_head":"\nMekanizmi i inteligjenc\u00ebs artificiale mund t\u00eb zbuloj\u00eb mutacione n\u00eb tumoret e trurit brenda 90 sekondave - Blogu i njoftimeve<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link 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