{"id":1896,"date":"2017-09-28T17:59:24","date_gmt":"2017-09-28T15:59:24","guid":{"rendered":"https:\/\/www.njoftime.co\/blog\/?p=1896"},"modified":"2017-09-28T18:00:30","modified_gmt":"2017-09-28T16:00:30","slug":"shkencetaret-heqin-gene-nga-embrioni-njerezor","status":"publish","type":"post","link":"https:\/\/www.njoftime.co\/blog\/shkencetaret-heqin-gene-nga-embrioni-njerezor.html","title":{"rendered":"Shkenc\u00ebtar\u00ebt p\u00ebr her\u00eb t\u00eb par\u00eb heqin Gene nga embrioni njer\u00ebzor"},"content":{"rendered":"<p><a href=\"https:\/\/www.njoftime.co\/blog\/wp-content\/uploads\/2017\/09\/embryo-625x352.png\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1897 alignleft\" src=\"https:\/\/www.njoftime.co\/blog\/wp-content\/uploads\/2017\/09\/embryo-625x352-300x169.png\" alt=\"\" width=\"300\" height=\"169\" srcset=\"https:\/\/www.njoftime.co\/blog\/wp-content\/uploads\/2017\/09\/embryo-625x352-300x169.png 300w, https:\/\/www.njoftime.co\/blog\/wp-content\/uploads\/2017\/09\/embryo-625x352.png 625w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a>Nd\u00ebrsa \u00ebsht\u00eb e leht\u00eb t\u00eb mendosh se njer\u00ebzit jan\u00eb akoma n\u00eb gjunj\u00eb, t\u00eb inxhinieris\u00eb gjenetike, por ne jemi n\u00eb t\u00eb v\u00ebrtet\u00eb vet\u00ebm n\u00eb fazat e saj t\u00eb fillimit, me kalime t\u00eb reja q\u00eb vijn\u00eb gjat\u00eb gjith\u00eb koh\u00ebs.<\/p>\n<p>Kjo tha, nj\u00eb ekip studiuesish ka njoftuar se ata kan\u00eb p\u00ebrdorur CRISPR p\u00ebr embrionet njer\u00ebzore p\u00ebr her\u00eb t\u00eb par\u00eb. Qendrat e tyre punojn\u00eb n\u00eb OCT4, nj\u00eb protein\u00eb e specializuar q\u00eb kodon nj\u00eb pjes\u00eb t\u00eb r\u00ebnd\u00ebsishme t\u00eb zhvillimit embrional. Por, titulli i v\u00ebrtet\u00eb \u00ebsht\u00eb se ne kemi marr\u00eb nj\u00eb hap t\u00eb ri, si nj\u00eb specie, p\u00ebr t\u00eb ndryshuar n\u00eb m\u00ebnyr\u00eb aktive informacionin gjenetik t\u00eb njeriut gjat\u00eb zhvillimit. CRISPR \u00ebsht\u00eb p\u00ebrdorur n\u00eb sprovat mbi t\u00eb rriturit e gjall\u00eb m\u00eb par\u00eb, por ajo ka sh\u00ebnjestruar vet\u00ebm pjes\u00eb t\u00eb vogla t\u00eb trupit.<\/p>\n<p>Kjo seri e eksperimenteve megjithat\u00eb ishte e para p\u00ebr\u00a0 ADN embrionale njer\u00ebzore me teknik\u00ebn. Kathy Niakin, nj\u00eb biolog zhvillimor me qend\u00ebr n\u00eb Lond\u00ebr ishte autori kryesor n\u00eb let\u00ebr. Ekipi i saj p\u00ebrdorte CRISPER p\u00ebr t\u00eb redaktuar OCT4 n\u00eb zygotes njer\u00ebzore &#8211; nj\u00eb faz\u00eb zhvillimi q\u00eb \u00ebsht\u00eb, teknikisht, para-embrionike. K\u00ebto ishin t\u00eb gjitha t\u00eb mbetura nga trajtimet in vitro dhe dhuruar nga \u00e7ifte.<\/p>\n<p>Eksperimentet, botuar k\u00ebt\u00eb jav\u00eb n\u00eb Natyr\u00eb, treguan se OCT4 luan nj\u00eb rol jet\u00ebsor n\u00eb zhvillim. Pa kopjet e funksionimit t\u00eb gjenit, embrionet n\u00eb zhvillim nuk arrit\u00ebn t\u00eb zhvillonin disa lloje t\u00eb qelizave kritike, si qelizat placentale, t\u00eb cilat jan\u00eb t\u00eb nevojshme p\u00ebr zhvillim.<\/p>\n<p>P\u00ebrs\u00ebri ky zbulim nd\u00ebrkoh\u00eb q\u00eb \u00ebsht\u00eb i fresk\u00ebt, merr nj\u00eb vendndodhje p\u00ebr zbulimin se CRISPR punon p\u00ebr t\u00eb studiuar zhvillimin e hersh\u00ebm. Kjo mund t\u00eb na jap\u00eb nj\u00eb rrug\u00eb t\u00eb re p\u00ebr t\u00eb studiuar gjith\u00e7ka nga s\u00ebmundjet kongjenitale dhe defektet e lindjes, se si ndodhin t\u00eb gjitha hapat e nd\u00ebrlikuar q\u00eb na krijojn\u00eb. Si\u00e7 v\u00ebrehet se\u00a0 \u00ebsht\u00eb gjithashtu nj\u00eb prov\u00eb e madhe p\u00ebr rregulloret e reja t\u00eb studimit t\u00eb embrionit n\u00eb Mbret\u00ebrin\u00eb e Bashkuar.<\/p>\n<p>Niakan d\u00ebrgoi aplikacionin e saj n\u00eb 2015, duke detajuar planin e saj dhe synimin e saj p\u00ebr t\u00eb p\u00ebrdorur CRISPR p\u00ebr t\u00eb studiuar rolin e OTT4 n\u00eb zhvillim. Dhe duket sikur kjo shkoi m\u00eb mir\u00eb se \u00e7dokush mund t\u00eb kishte shpresuar.<\/p>\n<p>&#8220;Ne konkludojm\u00eb se CRISPR &#8230; \u00ebsht\u00eb nj\u00eb metod\u00eb e fuqishme p\u00ebr t\u00eb hetuar funksionimin e gjeneve n\u00eb kontekstin e zhvillimit njer\u00ebzor&#8221;, thuhet n\u00eb let\u00ebr. Ashtu si apo jo, e ardhmja \u00ebsht\u00eb k\u00ebtu.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nd\u00ebrsa \u00ebsht\u00eb e leht\u00eb t\u00eb mendosh se njer\u00ebzit jan\u00eb akoma n\u00eb gjunj\u00eb, t\u00eb inxhinieris\u00eb gjenetike, por ne jemi n\u00eb t\u00eb v\u00ebrtet\u00eb vet\u00ebm n\u00eb fazat e saj t\u00eb fillimit, me kalime t\u00eb reja q\u00eb vijn\u00eb gjat\u00eb gjith\u00eb koh\u00ebs. Kjo tha, nj\u00eb ekip studiuesish ka njoftuar se ata kan\u00eb p\u00ebrdorur CRISPR p\u00ebr embrionet njer\u00ebzore p\u00ebr her\u00eb t\u00eb [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1897,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[278,206,488,250],"tags":[505,508,506,507],"class_list":{"0":"post-1896","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-bota","8":"category-kuriozitete","9":"category-life-style","10":"category-teknologji","11":"tag-adn","12":"tag-crisper","13":"tag-oct4","14":"tag-ott4"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Shkenc\u00ebtar\u00ebt p\u00ebr her\u00eb t\u00eb par\u00eb heqin Gene nga embrioni njer\u00ebzor - Blogu 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